A beautiful woman is married to a film director. Despite the apparent happiness of the marriage, she has an affair with a young womanizer, and flirts with a screenwriter. During the filming of a film directed by her husband, two actresses are mysteriously murdered.
Ofelia's wedding day is approaching and she is to be married to Eduaurdo. She has some pre-wedding jitters during a meeting with her lover Gustavo but decides to tie the knot anyways. On her wedding night, Gustavo shows up in their room, murders Eduardo, and proceeds to turn Ofelia into a vampire so that they can be together forever. In the present day 1960's, a group of young men and women take shelter in an abandoned lodge after their van breaks down. Soon, Ofelia appears and seduces one of the guys and meanwhile the girls go missing. It is up to the other guys to figure out what is happening and Ofelia must make a decision as to how much longer she can continue with her cursed life.
